General Cell Lines and Cell Cultures
Eurofins Discoverx PrecisION hKv12.2 Recombinant Stable Cell Line, 2 vials. (CYL3089)
The PrecisION hKv12.2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Kv12.2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Kv12.2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
ATCC Merck Pneumococcal polysaccharide powder Type 43 (d11A) 2mg
Purified pneumococcal polysaccharides are manufactured by Merck & Company for small-quantity distribution by ATCC. The pneumococcal powders include those types which are components of the current 23-valent vaccine against Streptococcus pneumoniae. Each of the polysaccharide antigens used in the polyvalent vaccine is extracted and purified separately. These vaccine products can be used to assay for type-specific antibodies, research immune responses and study immunodeficiencies.
Ace Glass, Inc. VACUUM LINE C VACUUM LINE C
Supplemental Vacuum Line with McLeod Gauge, for the ACE-Burlitch system. The ACE-Burlitch inert atmosphere system is designed for maximum convenience and versatility in the handling of air-sensitive compounds in conjunction with ACE no-air labware, or suitiably adapted conventional glassware.
Cayman Chemical THUNDRTotal MEK1 TRFRET C 4800
Sandwich TR-FRET immunoassay for semi-quantitative detection of Total MEK1 in cell lysates
Amsbio LLC NF-kB Leeporter™ GFP Reporter-HEK293 Cell Line
NF-kB Leeporter™ GFP Reporter-HEK293 Cell Line
Biochain Institute Inc Paraffin Tissue Section - Human Lung Tumor: Large Cell Carcinoma, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Eurofins Discoverx PathHunter CHO-K1 GPR3 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0626C2)
The PathHunter GPR3 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR3 and EA-tagged β-Arrestin-2. Activation of GPR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC HCT116-SLC35B3-KO-c9; Colorectal carcinoma; Human (Homo sapiens)
The HCT116-SLC35B3-KO-c9 cell line contains a -5 deletion in SLC35B3 gene and combined with the parental cell line and other HCT116 derivatives can be used in cancer drug screening.
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
Eurofins Discoverx PathHunter U2OS INSRb Functional Assay, 2 vials. (93-0466C3)
The PathHunter U2OS INSRb Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated INSRb dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged INSRb and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC Bilophila wadsworthia
Bilophila wadsworthia strain WAL 7959 [Lab 88-130H] is a whole-genome sequenced bacterial type strain that was isolated from a perforated appendiceal abscess. This organism is a strict anaerobe.
ATCC Pfizer Pneumococcal polysaccharide powder Type 2 (d2) 10mg
Purified pneumococcal polysaccharide type 2 is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal polysaccharide type 2 can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Eurofins Discoverx ChemiScreen α1A Adrenergic Receptor Membrane Preparation, 1 vial. (HTS087M)
The ChemiScreen α1A Adrenergic Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of ADRA1A surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx PathHunter DDR1 Functional Assay, 2 vials. (93-0894C3)
The PathHunter DDR1 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated DDR1 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged DDR1 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Eurofins Discoverx PathHunter CHO-K1 mADCYAP1R1 (PAC1) β-Arrestin Cell Line, 2 vials. (93-0594C2)
The PathHunter mADCYAP1R1 (PAC1) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. PACAP) based activation of mADCYAP1R1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mADCYAP1R1 and EA-tagged β-Arrestin-2. Activation of mADCYAP1R1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.